When the brain is triggered by a stressful situation, either physical or emotional, the hormone is released into the blood to do its work. It’s responsible for making your heart rate and blood pressure increase during the body’s natural fight or flight response. Noradrenaline also acts as a stress hormone and is widely used as a vasoactive agent that narrows blood vessels and increases blood pressure. It works by activating alpha 1 receptors that constrict the arteries and work to increase blood pressure so that blood flow returns to the heart.
It works as a neurotransmitter in the central nervous system and sympathetic nervous system, where it’s released from our noradrenergic neurons.Īs a neurotransmitter, norepinephrine sends signals between our nerve cells. Norepinephrine is synthesized from dopamine and released from the adrenal medulla into the brain. Catecholamines are released into the blood in response to both physical and emotional stress. Norepinephrine, also called noradrenaline, is a neurotransmitter that belongs to a class of compounds known as catecholamines.
The key is to keep these stress hormone levels in check by reducing daily stress levels, engaging in regular exercise and maintaining a healthy weight. Like all hormones, when norepinephrine levels become too low or too high, it can lead to health conditions, including anxiety, blood pressure changes, brain fog and difficulty sleeping. The hormone also works as a vasoconstrictor, and the FDA has approved its use for blood pressure control and as an adjunct in the treatment of cardiac arrest for people with severely low pressure. You’ve probably heard of adrenaline (or epinephrine) before, but what about another similar hormone called norepinephrine? Like adrenaline, it’s produced during the body’s natural “fight or flight” response and works as one of the body’s first responders to stressful situations.
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